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A new study has revealed that DNA can be assembled in a way we didn't know about before
Scientists have discovered a completely new method of DNA synthesis. Normally, DNA synthesis requires a DNA template that serves as a guide for proteins called DNA polymerases. However, a team from Stanford University has now discovered a new type of polymerase that can function even without a DNA template. In the bacterial defense system, DNA strands (orange and cyan) are synthesized by two enzymes: one (yellow) uses RNA (beige) as a template to guide the assembly of the nucleotide bases that make up DNA. The second and unusual enzyme (light blue) uses its own amino acids as a template. For decades, biology textbooks have stated a simple rule: DNA is created by copying a DNA template. After one enzyme unravels the DNA double helix into two separate strands, another enzyme, called polymerase, creates a complementary sequence for each strand, base by base. Simply put, this creates two copies of the original DNA. This is then translated into RNA, and that into proteins. Scientists refer to this direction of translation as the central dogma.
Cardiology from the Perspective of a Clinical Geneticist
Dr. Veronika Krulišová, M.D., Ph.D., has published a brief overview article in the journal *Acta Medicinae* that highlights the importance of genetics from a cardiological perspective.
The article is attached to this post.
Get tested for Mycoplasma genitalium—you might have it without even knowing it, and it could be a cause of infertility
Mycoplasma genitalium is a relatively common sexually transmitted infection about which little is known, as it often causes no symptoms. However, if left untreated, it can cause serious and long-term damage. And what’s worse, according to experts, is that it is becoming resistant to antibiotics. Mycoplasma genitalium affects both men and women, and although it is most commonly spread through unprotected vaginal or anal sex, transmission can also occur through contact between infected fingers and intimate areas.
Interview with the head of the GHC Genetics laboratory in Téma magazine
For years, colonoscopy has been one of the most effective methods for detecting colorectal cancer, but many patients fear the procedure and put off getting tested. Now, however, a new alternative is available: genetic testing using a blood sample. What does the future hold for this approach in conjunction with artificial intelligence? Renáta Michalovská, head of our molecular genetics and microbiology laboratory, discusses this in the latest issue of the weekly magazine Téma.
Listen to the podcast for the healthcare journal on predictive genetics
Viktor Furman, CEO of GHC Genetics, and Renáta Michalovská, head of the GHC Genetics laboratory, were guests on the Zdravotnický deník podcast, where they discussed with Tomáš Cikrt what predictive genetics actually offers today, its potential, and its clear limitations. In the podcast, they also addressed topics such as