TESTS OF KINSHIP AND DESCENT

TESTS OF KINSHIP AND DESCENT

DNA is the genetic information stored in the cells of our body and is a combination of the DNA of both of our biological parents. Therefore, when situations or circumstances arise in life that lead to the need to verify one's biological relationship with another person or persons, a DNA kinship test comes into play, which can be used to determine paternity, confirm maternity, consanguinity, as well as to determine the zygosity of twins or the origin of family lines.

Descent tests analyse DNA with so-called STR markers, which can confirm or exclude the relationship of the tested persons with certainty. We recommend that you approach kinship testing responsibly and after considering all the possible consequences that the results of such an analysis may have for the family. 

Sample collection is completely painless and takes no more than 5 minutes. It can be obtained by oral swab or blood collection. You can also swab your oral cavity in the comfort of your own home, then just send it to us by post. For blood collection, it is necessary for all people tested to come to our outpatient clinic. All tests can be performed anonymously if required. Our laboratory does not conduct paternity tests in cooperation with a court-appointed expert.

AncesTree®

Our unique test that allows you to retrace your ancestors' footsteps and find out information about family lines and their place of origin back several hundred generations. You will receive the final report including a certificate, pedigree map and detailed information about your DNA in original packaging. Also suitable as a gift.

This test has its own website with detailed information at ancestree.cz

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PapaGen®

The PapaGen® test is a genetic analysis performed to determine paternity (the biological relationship between a man and a child). It is the only way to confirm or exclude paternity with certainty. The test can also be used to check the possibility of organ donation or the risk of hereditary disease.

PapaGen®

4 000 Kč

MamaGen®

The MamaGen® test is a genetic analysis carried out to confirm maternity, i.e. whether a woman is the biological mother of a child or, conversely, whether a person is the child of his or her mother. The test can also be used to check the possibility of organ donation or the risk of hereditary disease.

MamaGen®

4 000 Kč

Familia

The Familia test is a genetic analysis performed to confirm a biological relationship. This test can also be used to confirm or exclude paternity without the direct involvement of the presumed father. In this way, paternity can be confirmed or ruled out by analysing the DNA of the father's parents, i.e. the child's grandparents.

Familia

6 700 Kč

Twin

DNA analysis which makes it possible to clearly determine whether twins are identical (monozygotic) or non-identical (dizygotic). Twins of different sex are very likely to be dizygotic.

Twin

4 500 Kč

HOW DOES THE WHOLE PROCESS WORK?

HOW DOES THE WHOLE PROCESS WORK?

After ordering the test, you will receive an email with detailed information. A DNA sample is most often obtained through an oral swab or blood sample. You can perform the oral swab yourself in the comfort of your own home using a collection kit which will be sent to you by mail together with instructions and other documents. You can have your blood drawn at your local physician's office or at our outpatient clinic. The result of the analysis will be sent to you by e-mail or by post as agreed. In the case of a positive result, we recommend an appointment for a genetic consultation. 

MOST REQUESTED TESTS

Comprehensive genetic analyses identify possible hereditary predispositions for a set of most common diseases. Based on the results, the level of risk for cardiovascular, cancer, metabolic, autoimmune and other diseases can be determined and appropriate preventive measures can be set in consultation with a doctor.

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REPRODUCTIVE GENETICS

Reproductive genetics allows to minimize the risks in family planning. Genetic analysis can be used to determine whether one or both of a couple carries a risky hereditary disposition that could cause serious diseases or birth defects in their offspring. It can clarify the cause of infertility or repeated miscarriages.

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HEART AND BLOOD VESSEL DISEASE

This area of genetic testing includes testing for hereditary predispositions to blood clotting disorders, which include thrombosis, myocardial infarction, stroke, atherosclerosis, high blood pressure and other genetic cardiovascular diseases.

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METABOLIC DISORDERS

Inherited metabolic disorders are caused by defects in enzyme-coding genes involved in metabolism. It is a rather diverse group of several hundred diseases with different manifestations, different types of inheritance and treatment options. As a result of poor metabolic function, metabolism is impaired, which can lead to severe organ damage. A large number of metabolic disorders result in health problems caused by the accumulation of substances that become toxic and interfere with the normal functioning of the body.

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GIFT VOUCHERS

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PHARMACOGENETICS

Pharmacogenetics is the study of how differences in our genes affect how drugs act on our bodies and how our bodies respond to those drugs. Genetic predispositions affect the rate of metabolic processing (activation or breakdown) of a drug, its concentration in the blood, the effectiveness of treatment and the risk of side effects. Based on this knowledge, the appropriate drug can be selected for a particular patient, the appropriate dose can be determined and the risk of side effects can be minimised.

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HEREDITARY CANCERS

Oncological disease, popularly known as cancer, is currently one of the most common diseases of affluence. Tumours arise from the uncontrolled proliferation of cells, which occurs randomly or as a result of an inherited mutation in a specific gene. According to the characteristics of the tumour and the prognosis of the disease, we distinguish between benign and malignant tumours, which are 10-15% hereditary. The most common cancers include breast and ovarian cancer, prostate cancer, colon cancer, pancreatic cancer, thyroid cancer and various types of leukaemia.

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OTHER HEREDITARY DISEASES

This group of genetic examinations is aimed at detecting the risk of hereditary and genetically determined diseases. This is both for the purpose of prevention (prediction) aimed at capturing genetic changes associated with the risk of developing a disease during life, for the purpose of diagnosis in persons with specific symptoms or manifestations of a disease, and last but not least, for the purpose of detecting possible transmission before family planning.

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GENETIC CONSULTATION

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PRENATAL DIAGNOSTICS

At GHC Genetics, we now offer 2 types of non-invasive prenatal testing (NIPT): Geneplanet Plus and Geneplanet Twins.

The non-invasive prenatal testing (NIPT) is designed for pregnant women. It can detect the risk of chromosomal defects such as Down's, Patau's and Edwards syndromes with an accuracy of more than 99%. This test, available from 9 weeks of pregnancy, is a gentle and reliable way to get key information about your baby's genetic health.

A comprehensive spectrum of prenatal examinations (including NIPT) and above-standard prenatal care and control of fetal health throughout the entire pregnancy is offered by our sister Centre of Prenatal Diagnostics PRENET in Pardubice. It performs biochemical screening for birth defects in the first and second trimesters, integrated screening for birth defects and non-invasive tests (NIPT). It also performs ultrasound screenings with the innovative Voluson E8 ultrasound machine, both in the first trimester (including NT, FMF certified sonographer) and also at 20 and 30 weeks of pregnancy, as well as targeted super-conciliar ultrasound. The prenatal centre also includes a genetics clinic.

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GENSCAN® – COMPREHENSIVE ANALYSIS

The propensity to certain diseases, but also how the body reacts to various risk factors and external influences, is stored in our DNA. GenScan® genetic analysis is aimed at detecting a wide range of health risks and the possibility of developing diseases of civilization. Whether and to what extent, if at all, the potential predispositions to develop a particular disease come to fruition over the course of a lifetime is influenced quite significantly by our lifestyle. Based on a comprehensive and detailed genetic analysis, GenScan® can reveal genetic predispositions to certain diseases, allowing you to focus your prevention and health care in the right direction and improve your quality of life.

The test is particularly suitable for those who want to maintain their health in the best possible condition in the long term. In addition to predispositions to hereditary and/or civilization diseases, the results of the analysis will also help to determine, for example, what lifestyle changes are specifically desirable for you, what laboratory values you should regularly monitor, which medications, if any, are most suitable for you and in what dosage, the cause of your difficulties in conceiving or recurrent illness in your family, and many others.

In our laboratory, physicians and geneticists with many years of experience are involved in developing tests, performing genetic analyses, and interpreting results. This allows us to provide you with a truly detailed view of your health and the highest level of care. We make sure that the results of the analysis are easy to understand and as beneficial to you as possible. A consultation with your doctor is an essential part of the examination, so that your personal medical history is taken into account when evaluating the results and the conclusions of the analysis are explained in a clear manner. This gives you a clear report on your health, a comprehensive set of personalised recommendations on how best to compensate for any risks, and answers to any questions you may have about your health. Improve your life - it's in your genes and in your hands.

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Hidden products

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Frequently Asked Questions

The time required for the laboratory examination (sample analysis) and the delivery date of the result vary according to the type and complexity of the examination. Usually it is in the order of weeks, for complex tests up to several months. The delivery date of the result is indicated in the details of each test on our website. In urgent situations, e.g. for a woman with a newly diagnosed breast or ovarian tumour before surgery, the oncopanel cancer test is performed in STATIM mode and the result is available within 3-4 weeks, whereas in normal mode it takes up to 6 months.
Health insurance always covers genetic consultations recommended by the attending physician (usually a general practitioner, paediatrician, oncologist, gynaecologist or other specialist). During the consultation, a clinical geneticist will assess whether the indication criteria for testing for the predisposition genes are met; if so, the entire genetic test, including laboratory analysis of the sample and subsequent consultation with the geneticist/doctor, is covered by health insurance. If the criteria for the genetic testing are not met, the patient can pay for the selected/recommended test as a self-payment.
After making an appointment, first fill out our personal and family history questionnaire HERE on our website. This is followed by a consultation with a doctor who will compile your three-generation family tree and decide on the indication for laboratory genetic testing. We also recommend that you bring medical reports from recent important examinations.
Recommendation – a referral from the doctor who recommended the genetic consultation. Medical reports from previous examinations related to the requested genetic test. It is not necessary to be fasting for the genetic examination, so you can easily make an appointment in the afternoon. Do not forget to fill out online genetic family and personal history questionnaire before your visit, which you can find HERE.
It has been reported that approximately 5-10% of cancers are caused by inborn changes in certain genes. One of the main goals of predictive genetic testing is the early identification of people at risk. If risk predispositions (gene mutations) are detected, preventive follow-up at specialised centres is recommended, where possible cancers are detected early and the chances of successful treatment are increased. In the case of high-risk mutations, preventive surgery may be recommended to make the risk of cancer in a given organ virtually impossible (for example, removal of the breast glands or removal of the uterus and ovary in BRCA1 or BRCA2 mutation carriers).
If your first-degree relative (parents, siblings, children) develops colon cancer before the age of 45, your risk of developing this cancer is 5 times higher. If you have three first-degree relatives, your risk can be as high as 50%. In families with a history of recurrent bowel cancer or with a history of bowel cancer at a young age, it could be hereditary cancer syndrome (Lynch syndrome). In such cases, genetic consultation is recommended.

Do you have a question or don't know which test to choose?

Call us at 800 390 390 or contact us and we'll be happy to help.