We have introduced Chronic Lymphocytic Leukemia (CLL) testing

We have introduced Chronic Lymphocytic Leukemia (CLL) testing

CLL is a cancer of the white blood cells (lymphocytes) that affects mostly elderly patients (>50 years) and almost exclusively Caucasians. It is the most common type of leukaemia in Europe. Men are affected twice as much as women. CLL is a disease that develops very slowly and is difficult to catch at an early stage.

It is most often diagnosed incidentally during a blood count. The first symptoms include painless enlargement of lymph nodes or nodes in the neck, groin or armpits, as well as abdominal pain and digestive discomfort. In the advanced stage, they include fever, night sweats, weight loss, general weakness and fatigue. The first diagnostic test is a biochemical blood count, followed by a haemato-oncological examination:

  • determination of IgVh mutation status

  • examination of 11q- (ATM), +12, 13q- (RB1, DLEU) and 17p- (TP53) genomic aberrations
      • these examinations are important to confirm the diagnosis and determine prognosis and subsequent treatment

      • the examination is performed from peripheral blood. Results are available within 10-15 working days