This area of genetic testing includes testing for immunogenetic diseases such as celiac disease (gluten intolerance), lactose intolerance (intolerance to dairy products), fructose intolerance (inability to metabolize fructose and other sugars), histamine intolerance and Bechterew's disease. Immunogenetics is a relatively young field of science, created by the intersection of immunology and genetics. It deals with the study of genetic conditioning of immune system components and genetic regulation of immune reactions.
Celiac disease is an autoimmune inflammatory systemic disease caused by gluten in certain cereals (and prolamins similar to it) in genetically susceptible individuals. The prevalence of celiac disease in the Czech Republic is 1 : 200 to 1 : 250, both men and women are affected (ratio 1 : 2).
Delivery time: 10 working days
Lactose intolerance means that the body's ability to digest milk sugar - lactose - is impaired. It is the most common form of disaccharidase deficiency. Primary lactose intolerance is essentially a normal physiological condition caused by a genetically reduced activity of the enzyme lactase (phlorizin hydrolase).
Delivery time: 10 working days
Hereditary fructose intolerance (HFI) is a rare but serious autosomal recessive inherited disease caused by the body's inability to metabolize fructose and similar sugars such as sucrose and sorbitol.
Delivery time: 10 working days
Histamine intolerance is an imbalance between the supply of histamine to the body and its degradation. This imbalance may be caused by increased dietary histamine intake, increased histamine production (e.g. in allergic reactions or bacterial infections), or insufficient histamine breakdown due to decreased activity of the enzyme diamine oxidase (DAO).
Delivery time: 10 working days
Ankylosing spondylitis, or Bechterew's disease, is an autoimmune rheumatic disease that causes chronic inflammation, especially in the joints of the spine. This disease affects men more often than women, at a rate of 3 : 1.
Delivery time: 10 working days