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Choose a specific test or make an appointment for a genetic consultation.
The screening test for the diagnosis of lung carcinoma from a patient’s blood sample is based on detecting biomarkers associated with the presence of lung cancer and malignant pulmonary nodules.
Detection is performed by identifying methylation of the SHOX2, RASSF1A, and PTGER4 genes using a highly sensitive Real-Time PCR method.
Why take the test?
Lung cancer is the leading cause of cancer-related deaths worldwide.
Early detection significantly improves treatment outcomes:
Five-year survival rate with early diagnosis: up to 92%
Five-year survival rate in advanced stages: only 5%
In early-stage lung cancer, epigenetic changes often occur in the form of DNA methylation. This test can identify such changes from a simple blood sample, without the need for invasive procedures.
Who is the test suitable for:
Preventively recommended for individuals aged 40 and over.
Smokers and passive smokers
Patients with a family history of lung cancer or other malignancies
Individuals with lung diseases (e.g., COPD, pulmonary fibrosis)
Patients with a pulmonary nodule or after lung cancer treatment (for recurrence monitoring)
People exposed to carcinogens at work or in the environment
Interpretation of results:
Positive result:
A low-dose CT (LDCT) scan is recommended, along with biopsy or other diagnostic methods as needed.
Contact center: MUDr. Jana Krejčí, Bulovka University Hospital (Department of Pulmonology)
Negative result:
If symptoms persist, consult your physician.
It is recommended to repeat the test after one year.
Choose a specific test or make an appointment for a genetic consultation.
A sample of your DNA obtained from a blood sample.
Our team of experienced professionals will analyse the sample using the latest methods and technologies.
After the test has been evaluated, you will receive a detailed and easy-to-understand laboratory report, or a consultation with a clinical geneticist will be recommended.