Lung carcinoma
Lung carcinoma
A non-invasive blood test enables early detection of lung cancer by identifying specific biomarkers. Early diagnosis significantly increases the chances of successful treatment — the five-year survival rate for early-stage cases reaches up to 92%. The test is suitable for smokers, individuals over 40, patients with lung diseases, or those with a family history of cancer.
DETAILED INFORMATION
The screening test for the diagnosis of lung carcinoma from a patient’s blood sample is based on detecting biomarkers associated with the presence of lung cancer and malignant pulmonary nodules.
Detection is performed by identifying methylation of the SHOX2, RASSF1A, and PTGER4 genes using a highly sensitive Real-Time PCR method.
Why take the test?
Lung cancer is the leading cause of cancer-related deaths worldwide.
Early detection significantly improves treatment outcomes:
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Five-year survival rate with early diagnosis: up to 92%
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Five-year survival rate in advanced stages: only 5%
In early-stage lung cancer, epigenetic changes often occur in the form of DNA methylation. This test can identify such changes from a simple blood sample, without the need for invasive procedures.
Who is the test suitable for:
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Individuals aged 40+
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Smokers and passive smokers
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Patients with a family history of lung cancer or other malignancies
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Individuals with lung diseases (e.g., COPD, pulmonary fibrosis)
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Patients with a pulmonary nodule or after lung cancer treatment (for recurrence monitoring)
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People exposed to carcinogens at work or in the environment
Interpretation of results:
Positive result:
A low-dose CT (LDCT) scan is recommended, along with biopsy or other diagnostic methods as needed.
Contact center: MUDr. Jana Krejčí, Bulovka University Hospital (Department of Pulmonology)
Negative result:
If symptoms persist, consult your physician.
It is recommended to repeat the test after one year.
You will receive the result within 15 working days.
How does the whole process work?
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Sampling
A sample of your DNA is most often obtained through an oral swab or blood sample.3
Analysis
Our team of experienced professionals will analyse the sample using the latest methods and technologies.4
Result
After the test has been evaluated, you will receive a detailed and easy-to-understand laboratory report, or a consultation with a clinical geneticist will be recommended.Frequently Asked Questions
It is a blood test that detects early stages of lung cancer by analyzing DNA.
Early detection significantly increases the chances of successful treatment.
People over 40, smokers, and individuals with lung risks or diseases.
The sample is collected from a blood draw.
It is recommended to repeat it once a year.