Colorectal cancer
Colorectal cancer
A non-invasive screening test allows for the detection of colorectal cancer (cancer of the colon and rectum) at an early stage, even before symptoms appear. The test works by detecting biomarkers in the patient’s blood and is suitable for individuals with risk factors or a family history of the disease. Early diagnosis significantly increases the chances of successful treatment.
DETAILED INFORMATION
The test is based on the detection of methylation of the Septin 9, SDC2, and BCAT1 genes in the patient’s circulating cell-free DNA. It is a highly sensitive Real-Time PCR method that can detect both colorectal cancer and precancerous changes.
Why is the test important?
Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer-related deaths. Early detection is crucial for improving patient survival. In the early stages, epigenetic changes are present, which the test can identify.
Who is the test suitable for:
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Individuals over 40 years old.
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Patients with blood in the stool, chronic inflammation of the colon, constipation, or hemorrhoids.
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Patients with a family history of colorectal cancer, adenomas, or hereditary forms of cancer.
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Patients with benign colorectal polyps or chronic ulcerative colitis.
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Patients with type II diabetes, smokers, and individuals with an unhealthy lifestyle.
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Patients after treatment for colorectal cancer (for recurrence monitoring).
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Individuals who refuse preventive colonoscopy.
Test parameters:
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Negative predictive value: 94.22 %
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Positive predictive value: 84.75 %
What the test results mean:
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Positive result: The patient is recommended to undergo a colonoscopy; contact: MUDr. Magdalena Stefanová, Na Františku Hospital (gastroenterology clinic).
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Negative result: If symptoms persist, consult a specialist; it is recommended to repeat the test in 1 year.
Result delivery time: 15 working days
You will receive the result within 15 working days.
How does the whole process work?
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Sampling
A sample of your DNA is most often obtained through an oral swab or blood sample.3
Analysis
Our team of experienced professionals will analyse the sample using the latest methods and technologies.4
Result
After the test has been evaluated, you will receive a detailed and easy-to-understand laboratory report, or a consultation with a clinical geneticist will be recommended.Frequently Asked Questions
It detects colorectal cancer at an early stage, even before symptoms appear.
For individuals over 40 years old, with a family history of cancer, blood in the stool, intestinal inflammation, polyps, diabetes, smokers, and people with an unhealthy lifestyle.
People at higher risk of cancer, such as those with a family history, chronic intestinal issues, or previous treatment for colorectal cancer.
It is recommended to repeat the test annually if the result is negative.
The result is available within 15 working days.