Kardiogen®

Kardiogen®

Reveals the risk of cardiovascular disease

The CardioGen® test can detect the risk of cardiovascular disease before the first clinical symptoms appear. Cardiovascular disease, or heart and blood vessel disease, is one of the so-called genetically determined diseases of affluence, the likelihood of which increases with age. Therefore, prevention plays a crucial role here. 

Kardiogen®
3 500 Kč
WHEN DO I RECEIVE THE RESULT?

WHEN DO I RECEIVE THE RESULT?

Within 10 working days after receipt of your sample.

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HOW THE SAMPLE IS TAKEN

HOW THE SAMPLE IS TAKEN

By oral swab or blood collection.

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FREQUENTLY ASKED QUESTIONS

FREQUENTLY ASKED QUESTIONS

An overview of your most frequently asked questions and our answers.

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IN WHICH SITUATIONS IT IS APPROPRIATE TO TAKE THE TEST

DETAILED INFORMATION

DETAILED INFORMATION

Cardiovascular diseases are often caused by the interaction of external risk factors and hereditary predispositions. The two main diseases of the cardiovascular system are atherosclerosis, or the corrosion and gradual clogging of blood vessels, and venous thrombosis, or the formation of blood clots. Atherosclerosis is not just the deposition of fat in blood vessels, it is an inflammatory process that impairs their elasticity. These diseases can subsequently lead to hypertension, thrombosis, pulmonary embolism, limb ischemia, myocardial infarction, cerebral stroke and many other serious health complications.

External risk factors for cardiovascular disease include smoking, lack of physical inactivity, obesity, prolonged stress and inappropriate diet. Age and gender also play a role: while men's risk of cardiovascular disease increases after the age of 45, women's risk increases after the age of 55, usually after menopause, when atherosclerotic changes accelerate due to a decline in female hormones.

The KardioGen® genetic analysis identifies gene variants that have the greatest influence on the development of different forms of heart and blood vessel disease. Although the genetic predisposition to the disease cannot be changed, the risks associated with the identified hereditary predisposition can be minimised by appropriate preventive measures. Therefore, prevention plays a crucial role here. In addition, the function of all organs in the body, i.e. our overall health, depends on the condition of the heart and blood vessels.

You will receive the result within 10 working days.
HOW DOES THE WHOLE PROCESS WORK?

HOW DOES THE WHOLE PROCESS WORK?

After ordering the test, you will receive an email with detailed information. A DNA sample is most often obtained through an oral swab or blood sample. You can perform the oral swab yourself in the comfort of your own home using a collection kit which will be sent to you by mail together with instructions and other documents. You can have your blood drawn at your local physician's office or at our outpatient clinic. The result of the analysis will be sent to you by e-mail or by post as agreed. In the case of a positive result, we recommend an appointment for a genetic consultation. 

Frequently Asked Questions

The time required for the laboratory examination (sample analysis) and the delivery date of the result vary according to the type and complexity of the examination. Usually it is in the order of weeks, for complex tests up to several months. The delivery date of the result is indicated in the details of each test on our website. In urgent situations, e.g. for a woman with a newly diagnosed breast or ovarian tumour before surgery, the oncopanel cancer test is performed in STATIM mode and the result is available within 3-4 weeks, whereas in normal mode it takes up to 6 months.
Health insurance always covers genetic consultations recommended by the attending physician (usually a general practitioner, paediatrician, oncologist, gynaecologist or other specialist). During the consultation, a clinical geneticist will assess whether the indication criteria for testing for the predisposition genes are met; if so, the entire genetic test, including laboratory analysis of the sample and subsequent consultation with the geneticist/doctor, is covered by health insurance. If the criteria for the genetic testing are not met, the patient can pay for the selected/recommended test as a self-payment.
After making an appointment, you will come to our office where you will first fill out a personal and family history questionnaire, or you can download it from here on our website and fill it out in advance, in the comfort of your own home. Remember to bring it with you afterwards. This is followed by a consultation with a doctor who will compile your three-generation family tree and decide on the indication for laboratory genetic testing. We also recommend that you bring medical reports from recent important examinations.
Recommendation - a referral from the doctor who recommended the genetic consultation. Alternatively, a completed genetic family and personal history questionnaire, which can be downloaded here. However, the questionnaire can also be completed after you arrive at our office. Medical reports from previous examinations related to the requested genetic test. It is not necessary to be fasting for the genetic examination, so you can easily make an appointment in the afternoon.
It has been reported that approximately 5-10% of cancers are caused by inborn changes in certain genes. One of the main goals of predictive genetic testing is the early identification of people at risk. If risk predispositions (gene mutations) are detected, preventive follow-up at specialised centres is recommended, where possible cancers are detected early and the chances of successful treatment are increased. In the case of high-risk mutations, preventive surgery may be recommended to make the risk of cancer in a given organ virtually impossible (for example, removal of the breast glands or removal of the uterus and ovary in BRCA1 or BRCA2 mutation carriers).
If your first-degree relative (parents, siblings, children) develops colon cancer before the age of 45, your risk of developing this cancer is 5 times higher. If you have three first-degree relatives, your risk can be as high as 50%. In families with a history of recurrent bowel cancer or with a history of bowel cancer at a young age, it could be hereditary cancer syndrome (Lynch syndrome). In such cases, genetic consultation is recommended.

Do you have a question or don't know which test to choose?

Call us at 800 390 390 or contact us and we'll be happy to help.